55year old male H/o 12 days of fever,DENGUE IGM +ve With ACUTE ISCHEMIC STROCKE OF LEFT FRONTAL LOBE SECONDARY TO ? POST SPD TRANSFUSION ? DENGUE VASCLITIS RIGHT UMN FACIAL PALSY



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I have been given this case to solve in an attempt to understand the topic of " Patient clinical data analysis" to develop my competancy in reading and comprehending clinical data including history, clinical finding, investigations and come up with a diagnosis and treatment plan.came to the hospital with

CHEIF COMPLAINTS of fever since 12 days and burning micturation since 12 days 

HOPI

A 65 year old male ,apparently asymptomatic 12 days back then he had gradual onset of fever since 12 days initially  high grade fever associated  with chills, history  of burning micturition on day 3 of illness. Patient sought for consultation at local Rmp and treated with oral medication.  On day 4 of illness, the patient was brought to another local hospital  for further management,  there he was treated with iv Fluids for 3days. 

As fever didn't subside, patient was shifted  to another hospital; there he was treated with IV antibiotics  and 1 unit of platelet  transfusion  was done in view of low platelet count. During the transfusion  of platelet  patient had chills. From next day of transfusion  patient developed  slurred speech and was reffered to our hospital  in view of hemodialysis 

Past history: n/k/c/o dm ,htn, asthama,epilepsy.

Histroy  of platelet transfusion  on 24/10/22

Personal history:

Diet : mixed

Appetite decreased

Bowel and bladder movements - constipation since 3 days 

Consumes alcohol 180ml once in 2 weeks stopped since 6yrs

Smokes bedi 7 per day since age of 20 yrs

Family history- insignificant

General physical examination 

Patient conscious, Oriented to time ,and persons but not to place on day  of admission

 pallor +

No icterus,CYANOSIS, clubbing, lymphadenopathy , oedema of feet

Vitals

Temp :99°f

Pulse rate:86 bpm

Resp.rate- 16cpm

Bp- 130/80mmhg

Spo2-95%RA

GRBS:253mg/dl

SYSTEMIC EXAMINATION

CVS:

S1, S2 +, no thrills and murmurs

RS: BAE+, no added sounds heared

PER ABDOMEN-   scaphoid, umbilicus central inverted , no scars and sinusess, all quadrants moving with respiration, soft , non tender ,bowelsounds +

CNS examination: patient was Conscious , and oriented to time and person but not place on the day of admission 

Slurred speech  on the day of admission but improved on day 2 

All Cranial nerves intact , except for 7th cranial nerve 

 Deviation of mouth towards right 

Tongue fasiculations present 

Wrinking more on right than left

Sensory system examination:

B/l touch crude &fine, temperature, pain  and vibrations present

Motar system examination

 Reflexes were absent on the day of admission

Tone hypertonia in both upper and lower limbs 

Right greater than left



Gait short stepping  gait



Investigations:

 Xray

MRI

USG abdomen and pelvis

Ecg
2d echo
 
COURSE IN HOSPITAL:
A 65 YR MALE PRESENTED TO CASUALITY WITH ABOVE MENTIONED COMPLAINTS , UPON ADMISION INTIAL NEUROLOGIAL EXAMINATION SHOWED RIGHT SIDED WEAKNESS AND SAME SIDE FACIAL PALSY.
MRI BRAIN PROTOCOL WAS PERFORMED  AND SHOWED IMPRESSION OF  ACUTE LEFT FRONTOL LOBE INFRACT. NECESSARY NVESTIGATIONS WERE DONE. HIS HEMOGRAM ON ADMISSION WAS HB 9.3, TLC 3500 ,PLT 1.69L/CUMM  WITH IMPRESSION OF NORMOCYTIC NORMOCHROMIC ANEMIA WITH LEUKOPENIA.
 DAY 2 HB 9.1, TLC 4000, PLT 2.2 L/CUMM WITH IMPRESSION OF NORMOCYTIC NORMOCHROMIC ANEMIA .
DAY 3 HB 9.1 TLC 4800 PLT 1.68 L/CUMM WITH IMPRESSION OF NORMOCYTIC NORMOCHROMIC ANEMIA .
DAY 4 HB 9.9 TLC 4900 PLT 1.80 L/CUMM WITH IMPRESSION OF NORMOCYTIC NORMOCHROMIC ANEMIA. PATIENT WAS FOUND TO BE HAVING FBS: 247, PLBS 370, HBA1C 7.2 FOR  WHICH  HE WAS STARTED ON INSULIN AND HIS BLOOD SUGARS WERE MONITORED, LATER FROM INSULIN PATIENT WAS GIVEN OHAS. DURING HIS STAY HE WAS  TREATED WITH ANTI PLATELETS,  ANTIPYRETICS,   IV FLUIDS AND OTHER SUPPORTIVE MEDICATIONS, PHYSIOTHERAPY  WAS ADVICED TO IMPROVE TONE.  DURING STAY HIS HYPERTONIA ,  REFLEXES AND GAIT IMPROVED.

  DIAGNOSIS: 

H/o DENGUE IGM +ve 

With ACUTE ISCHEMIC STROCKE OF LEFT FRONTAL LOBE SECONDARY TO ? POST SPD  TRANSFUSION 

? DENGUE VASCLITIS

RIGHT UMN FACIAL PALSY

HYPERKALEMIA (resolved)

WITH NON OLIGURIC AKI ( resolved)

Mild anemia

WITH DENOVO DM II

CAD TO LCX ,LAD[6yrs ago]


Treatment: 

 INJ ZOFER 4MG IV/BD

INJ NEOMOL IF TEMP  GREATER THAN 101 F

TAB ECOSPRIN 75 MG PO/ BD

TAB ATORVAS 40MG /PO/OD

TAB DOLO 65O MG PO/TID

TAB PAN 4O MG PO/OD

TAB METFORMIN 500 MG/PO /OD 

SYRUP ARYSTOZYME 15ML/PO/ TID

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