45 /F with ascitis under evaluation.

This E blog also reflects my patient centered online learning portfolio and your valuable inputs on the comment box is welcome.

I have been given this case to solve in an attempt to understand the topic of  " patient clinical data analysis" to develop my competency in reading and comprehending clinical data including history, clinical findings, investigations and come up with diagnosis and treatment plan.

45 year old woman , agricultural labourer by occupation came to the opd with 

CHIEF COMPLAINTS:
- Abdominal distension since 2 month 
- Decreased appetite since 1 month 
- Loss of weight since 2 month 
- Bilateral pedal edema since 5 days

HISTORY OF PRESENT ILLNESS :

Patient was apparantly asymptomatic 2 month back then she developed abdominal distension , which is insidious in onset and gradual in progression . 

Abdominal distension was associated with abdominal discomfort, loss of appetite and gradual weight loss up to 4_5 kgs ?  since  month 

With this  complaints,she went a near by hospital where USG abdomen was done.Usg revealed moderate amount of ascitis for which she was given conservative management   which is unknown  for 20 days.she also found to have low hb ,low serum k+ and low calcium levels and adviced to use iron sucrose tablets and vitamin D (tab shelcal  PO/OD) for 20 days. 

Even after taking theconservative  abdominal distension has not subsided hence she once again went to hospital where a repeat USG was done revealing gross ascitis. Her Hb, serum potassium and vit d levels were still found to be low , for which she was reffered to o

She also complains of  Bilateral pedal edema ,which is of pitting type and gradually progressive extending up to knee and subsiding after taking rest & aggravating on walking since 3 days 

PAST HISTORY :
Not a known case DM, HTN, TB, CVA, EPILEPSY.

PERSONAL HISTORY :
Diet - Mixed
Sleep- adequate 
Appetite -decreased 
Bowel and bladder movements -regular 
No addictions 

FAMILY HISTORY : 
Her father & mother were k/c/o TB , and both expired 10 years back 

MENSTRUAL HISTORY : 
Age at menarche - 13 years
LMP - 4 years back 
Before 4 years 
- Cycles were regular 
- 28 days cycle/3-5 days of flow 
- Uses 3 pads/day 
- Not associated  with clots.

GENERAL EXAMINATION :
Patient is conscious, coherent and cooperative  and well oriented to time place and person .
Moderately built and moderately nourished 
PALLOR  - PRESENT
# BILATERAL PEDAL EDEMA OF PITTING TYPE              PRESENT
 Icterus -absent
Clubbing- absent
 Cyanosis - absent
 Koilonychia-absent
Generalised lymphadenopathy  -absent

VITALS :
Temp: Afebrile 
PR: 80 bpm  
BP: 140/100 mm hg 
RR: 15 cpm  
Spo2 - 95% at RA  
GRBS - 124 mg/dl  
SYSTEMIC EXAMINATION 
CVS :
Inspection:
Chest wall is bilaterally symmetrical. 
No precordial bulge 
Palpation: 
JVP - normal 
Apex beat - felt in the left 5th intercostal space in the mid clavicular line. 
Auscultation: 
S1, S2 heard , No murmurs 

RESPIRATORY SYSTEM:
Position of trachea: central 
Bilateral air entry + 
Decreased breath sounds on right side 
No added sounds. 

PER ABDOMEN :
Inspection:
Shape of abdomen - ovoid 
Abdomen is distended , umbilicus inverted. 
Fullness of flanks present 
Abdominal striae present
No dilated veins,scars or sinuses 
No visible pulsations 
No hernial orifices 
Palpation : no tenderness 
Percussion:
DULL NOTE present in flanks
SHIFTING DULLNESS +
Fluid thrill absent  
Auscultation: 
Bowel sounds heard 

INVESTIGATIONS :
Hemogram
Hb:  8.3 gm/dL 
TLC:  2,800 cells/cu mm 
Neutrophils: 60% 
Lymphocytes: 28 % 
PCV - 24.8 vol % 
MCV - 76.5 fl 
MCHC - 33.5% 
MCH - 25.6 pg 
RBC: 3.24 millions/cu mm 
Platelets: 1 lakh cells/cu mm 
Blood grouping & Rh typing - A +ve


ESR- 95mm /1st hr

RETICULOCYTE COUNT -0.6%

 Corrected RC count- 0.3%



Coagulation profile
PT - 16 
INR - 1.11 
APTT - 33 



 

Complete urine examination
Albumin: trace 
Sugars: nil 
PC: 3-4 
EC: 2-3 
RBC: 4-5

RENAL FUNCTION TEST : 
Serum creatinine: 0.9 mg/dl 
Urea - 24 mg/dl 
Sodium  - 133 meq/l 
K+ - 3.0 meq/l 
Cl-  92 meq/l






LIVER FUNCTION TEST :
Total bilirubin: 1.21 mg/dl 
Direct bilirubin: 0.53 mg/dl 
SGOT: 10 IU/l 
SGPT: 10 IU/l 
ALP: 207 IU/l 
Total protein: 6.9 gm/dl 
Albumin: 3.6 gm/dl 
A/G: 1.08 




RBS-159mg/dl                                  


Serology - negative


 

ASCITIC FLUID ANALYSIS :Cell count and type



 
Volume - 2ml 
Color - yellow 
Appearance - clearr
TC - 55 cells 
Lymphocytes - 70% 
Neutrophils - 30% 
RBC - present 

Serum albumin - 3.6 gm/dl 
Ascitic albumin - 2.7 gm/dl 
SAAG - 0.9 
Serum LDH - 151 IU/l 
Ascitic fluid :
- LDH - 93 IU/l 
protein - 4.8 gm/dl 
- Sugar - 154 mg/dl 
Ascitic fluid ADA - 19 U/l

CHEST X RAY - PA view

ECG 


USG Abdomen   
 
 Impression- gross ascitis   



2D ECHO


30/8/21 HEMOGRAM 




*COOMBS TEST 
 
Direct coombs : positive (1+)
Indirect  coombs:positive (2+)


*1/09/21

Hemogram
Hb: 9.7 gm/dL 
TLC: 2,200 cells/cu mm 
Neutrophils: 60% 
Lymphocytes: 25 % 
PCV - 29.8 vol % 
MCV - 76.0 fl 
MCHC - 33% 
MCH - 25.1 pg 
RBC: 3.87 millions/cu mm 
Platelets: 1 lakh cells/cu mm

 SERUM ELECTROLYTES
Na- 135 meq/l
K- 3.7 meq/l
Cl-92 meq/l
 

Peripheral smear

RBC - Normocytic normochromic
WBC - within normal limits
Platelets - Adequate

 ASCITIC FLUID CULTURE AND SENSITIVITY REPORT

2/08/21
 
MOUNTOUX TEST - NEGATIVE  after 72 hrs 

CBNAAT- NEGATIVE  for TB

ASCITIC FLUID ANALYSIS (REPEAT)


CYTOLOGY 

PROVISIONAL DIAGNOSIS
  
? ASCITIS (EXUDATIVE TYPE ) UNDER EVALUATION

? TUBERCULAR ASCITIS


FEVER CHARTING

 TREATMENT


 TREATMENT


1. Fluid restriction <1 litre/day

2. Salt restriction <2gm /day

3. Tab LASIX 40 mg PO/BD

4. Tab ALDACTONE 25 mg PO/OD

5. Daily abdominal girth & weight monitoring

6. BP charting 6 hrly

Pedal edema decreased------》resolved by day 4 of the treatment 
Appetite   decreased --------》improved by day 3






1. Fluid restriction <1 lt/day

2. Salt restriction < 2g/day

3. Tab LASIX 40 mg /PO/BD

4.Tab ALDACTONE 25 mg/PO/OD

5. Daily AG and weight monitoring

6. Bp charting 6th hourly







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