CARDIOLOGY 3f
What is the evolution of the symptomatology in this patient in terms of an event timeline and where is the anatomical localization for the problem and what is the primary etiology of the patient's problem? Ans: Facial puffiness ( since 2 to 3 yrs) Sob grade 2( 1yr ago) Sob grade 2( 2days back again) Sob grade 4 Decreased urine output ( since 2 days) Anuria (since morning) 2. What are mechanism of action, indication and efficacy over placebo of each of the pharmacological and non pharmacological interventions used for this patient? Ans: Dobutamine MOA: acts on beta 1 receptor Beta1 ionotropic effect → increases heart contractility → increases cardiac output Indications are cardiogenic shock , Reversible heart failure Digoxin MOA: Digoxin has two principal mechanisms of action which are selectively employed depending on the indication: Positive Ionotropic: It increases the force of contraction of the heart by reversibly inhibiting the activity of the myocardial Na-K ATPa...